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赵亚杰

赵亚杰

人员介绍

个人简介

赵亚杰,男,博士,副教授,中共党员,硕士生导师,zhaoyajie@henu.edu.cn

 

教育经历

2012.09-2016.06 河南师范大学生命科学学院,生物技术,理学学士

2016.09-2022.01 中国农业大学农学院,作物生理学,硕博连读,农学博士

2020.01-2020.07 加州大学戴维斯分校,国家公派联合培养,Bruce D. Hammock院士

 

工作经历

2022.02-至今 河大一附院及抗体药物开发技术国家地方联合工程实验室

 

研究方向

基于纳米抗体的药物及诊断试剂开发

 

主持或参加的科研课题

国家重点研发计划,高质量纳米抗体基因资源库的构建和筛选技术研究,2019.4-2021.12,参与

河南省高等学校重点科研项目计划,基于TRAIL纳米抗体的脑梗死治疗药物开发,2024.1-2025.12,主持

河南省自然科学青年基金,CPPs-Nb19融合蛋白穿透血脑屏障治疗缺血性脑卒中的作用机制研究,2025.1-2026.12,主持

横向课题,抗D,E和F抗原纳米抗体开发,2025.9-2028.9,主持

 

获奖情况

2024年第二届河南省博士后创新创业大赛创新赛,优胜奖

 

发表的期刊论文

[1] Qingqing He, Yujie Chen, Zhaoxiang Wang, Simin Shen, Yajie Zhao, Haiyan Xing, Jiaqi Zhang, Yixuan Wu, Xueqin Zhang, Baomin Wang. Efficient Selection of the 2,4-Dichlorophenoxyacetic Acid Nanobody Gene from the Phage Library Constructed with Sorted Specific Cells and Expression in Plants to Confer Herbicide Resistance. Journal of Agricultural and Food Chemistry, 2024, 72(50): 27850−27860.

[2] Man Zhang, Xiaojiao Chen, Yajie Zhao, Jiaqi Zhang, Qingqing He, Jingqi Qian, Guiyu Tan, Wei Liu, Xiaoling Yang, Baomin Wang. Quantification of six types of cytokinins: Integration of an ultra-performance liquid chromatographic-electrospray tandem mass spectrometric method with antibody based immunoaffinity columns equally recognizing cytokinins in free base and nucleoside forms. Journal of Chromatography A, 2022, 1682: 463497.1-463497.10.

[3] Yajie Zhao, Mian Wang, Man Zhang, Xiaolin Yang, ZhenFeng Li, Natalia Vasylieva, Guiyu Tan, Baomin Wang, Bruce D. Hammock. Development of monoclonal antibody-based direct competitive enzyme-linked immunosorbent assay for the sensitive and accurate quantitation of sodium saccharin residue in food. Journal of Food Science, 2021, 86(8): 3720-3729.

[4] Guiyu Tan, Yajie Zhao, Mian Wang, Xiaojiao Chen, Baomin Wang, Qing X Li. Ultrasensitive quantitation of imidacloprid in vegetables by colloidal gold and time-resolved fluorescent nanobead traced lateral flow immunoassays. Food Chemistry, 2020, 311: 126055.1-126055.7.

[5] Yajie Zhao, Guiyu Tan, Mian Wang, Huan Lin, Lishan He, Lingyun Li, Baomin Wang. Application of Immunoassays for Rapid Monitor of Carbofuran Residue in Vegetables. Journal of Food Science, 2019, 84(11): 3296-3302.

 

专利

抗TRAIL纳米抗体及其应用,国家发明专利,中国,2025-04-11公开,赵亚杰,马远方,张海龙,魏寅祥,郭文锋,肖楚婷,公开号:CN119798441A。

一种抗AAV9纳米抗体及其应用,国家发明专利,中国,2025-08-08公开,赵亚杰,任兰洁,肖楚婷,郭文锋,张丽公开号:CN120441688A。